HSDiagnomics is constantly looking for interesting projects with partners from academia or companies. We are carrying out a number of research projects with focus on cancer and diseases with autoimmune background.


Publications since 2014 with a significant contribution by people from HSDiagnomics are listed below.


  • Abnormally differentiated CD4+ or CD8+ T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency.    Rensing-Ehl A, Völkl S, Speckmann C, Lorenz MR, Ritter J, Janda A, Abinun M, Pircher H, Bengsch B, Thimme R, Fuchs I, Ammann S, Allgäuer A, Kentouche K, Cant A, Hambleton S, Bettoni da Cunha C, Huetker S, Kühnle I, Pekrun A, Seidel MG, Hummel M, Mackensen A, Schwarz K, Ehl S.  Blood. 2014 Aug 7;124(6):851-60.
  • A new method to prevent carry-over contaminations in two-step PCR NGS library preparations.    Seitz V, Schaper S, Dröge A, Lenze D, Hummel M, Hennig S.   Nucleic Acids Res. 2015 Jul 7. <Free article
  • Donor CD4 T Cell Diversity Determines Virus Reactivation in Patients After HLA-Matched Allogeneic Stem Cell Transplantation.     Ritter J, Seitz V, Balzer H, Gary R, Lenze D, Moi S, Pasemann S, Seegebarth A, Wurdack M, Hennig S, Gerbitz A, Hummel M.   Am J Transplant. 2015 Aug;15(8):2170-9.
  • The ORFeome Collaboration: a genome-scale human ORF-clone resource.      Wiemann S, Pennacchio C, Hu Y, Hunter P, Harbers M, Amiet A, Bethel G, Busse M, Carninci P, Dunham I, Hao T, Harper JW, Hayashizaki Y, Heil O, Hennig S, Hotz-Wagenblatt A, Jang W, Jöcker A, Kawai J, Koenig C, Korn B, Lambert C, LeBeau A, Lu S, Maurer J, Moore T, Ohara O, Park J, Rolfs A, Salehi-Ashtiani K, Seiler C, Simmons B, van Brabant Smith A, Steel J, Wagner L, Weaver T, Wellenreuther R, Yang S, Vidal M, Gerhard DS, LaBaer J, Temple G, Hill DE.    Nat Methods. 2016 Feb 25;13(3):191-2.
  • A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma.     Joosten M, Ginzel S, Blex C, Schmidt D, Gombert M, Chen C, Linka RM, Gräbner O, Hain A, Hirsch B, Sommerfeld A, Seegebarth A, Gruber U, Maneck C, Zhang L, Stenin K, Dieks H, Sefkow M, Münk C, Baldus CD, Thiele R, Borkhardt A, Hummel M, Köster H, Fischer U, Dreger M, Seitz V.    Mol Oncol. 2016 Oct;10(8):1232-44.
  • T-cell repertoires in refractory coeliac disease. Ritter J, Zimmermann K, Jöhrens K, Mende S, Seegebarth A, Siegmund B, Hennig S, Todorova K, Rosenwald A, Daum S, Hummel M, Schumann.  Gut. 2017 Feb 10. Feb 10. [Epub ahead of print] PubMed PMID: 28188172.    <Free article>